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5-HTP

Basic Information

Summary

The precursor to serotonin. In some countries it is sold OTC as a supplement for mood stabilisation and insomnia. It is frequently used as a recovery supplement following the use of MDMA or any other drug that depletes serotonin. Do not mix this drug with anything serotonergic, as this can cause serotonin syndrome.

Common

Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.

Dose

Therapeutic
Common50-100mg
Sleep
Common100-200mg
Recovery
Common200-300mg

NOTE: Do not take this while on a serotonergic drug, only afterwards. Wait at least 12 hours following the last dose in the case of MDMA.

Duration

All ROAs
Onset30-60 minutes
Duration4-6 hours

Effects

sleep aid, antidepressant, appetite suppressant, nausea, mood stabilising

Avoid

Anything which interacts with serotonin. Including SSRIs, MAOIs, DXm, MDMA (during or before)

Aliases

5htp
5-hydroxytryptophan
tryptophan
l-tryptophan
oxitriptan

Mdma

5-HTP should only be taken at least 12 hours following an MDMA dose. Do not take it during or before MDMA - this can cause serotonin syndrome.

See TripSit Wiki for more information about drug interactions

Interactions

No interaction information for 5-HTP