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5-HTP

Basic Information

Summary

The precursor to serotonin. In some countries it is sold OTC as a supplement for mood stabilisation and insomnia. It is frequently used as a recovery supplement following the use of MDMA or any other drug that depletes serotonin. Do not mix this drug with anything serotonergic, as this can cause serotonin syndrome.

Common

Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.

Dose
Therapeutic
Common50-100mg
Sleep
Common100-200mg
Recovery
Common200-300mg

NOTE: Do not take this while on a serotonergic drug, only afterwards. Wait at least 12 hours following the last dose in the case of MDMA.

Duration
All ROAs
Onset30-60 minutes
Duration4-6 hours
Effects

    Effects lovingly provided by PsychonautWiki

    Effectssleep aid, antidepressant, appetite suppressant, nausea, mood stabilising
    AvoidAnything which interacts with serotonin. Including SSRIs, MAOIs, DXm, MDMA (during or before)
    Aliases5htp
    5-hydroxytryptophan
    tryptophan
    l-tryptophan
    oxitriptan
    Mdma5-HTP should only be taken at least 12 hours following an MDMA dose. Do not take it during or before MDMA - this can cause serotonin syndrome.
    See TripSit Wiki for more information about drug interactions

    Interactions

    No interaction information for 5-HTP