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5-MeO-DMT

Basic Information

Summary

A powerful psychedelic tryptamine found in many species of plants and some toad venom, with a history of use by native South Americans spanning thousands of years. Has similar qualities to DMT and related tryptamines. Very potent. Orally active in combination with an MAOI.

Psychedelic

Psychedelics are drugs which alter the perception, causing a number of mental effects which manifest in many forms including altered states of consciousness, visual or tactile effects.

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Research Chemical

Research chemicals are drugs with relatively little history of human use, and thus particular care should be taken if choosing to ingest them.

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Dose

Smoked
Light2-5mg
Strong10-20mg
Insufflated
Light3-5mg
Common5-10mg
Strong8-15mg

Duration

Smoked
Onset0-1 minutes
Duration5-15 minutes
After-effects1-2 hours
Insufflated
Onset1-5 minutes
Duration15-45 minutes
After-effects1-3 hours

Aliases

5meodmt
toads
5-meo
5meo
5-medmt

Effects

Smoked: short duration, powerful rushing of sensation, overwhelming fear, panic, experience of "the void", ego death

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Interactions

Dangerous

Unsafe

  • DXM
    • Little information exists about this combination.
  • Amphetamines
    • The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.
  • Cocaine
    • The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.
  • Tramadol

Caution

  • Mescaline
    • The 5-MeO class of tryptamines can be unpredictable in their interactions
  • DOx
    • The 5-MeO class of tryptamines can be unpredictable in their interactions, particularly increasing the risk of unpleasant physical side effects.
  • NBOMes
    • The 5-MeO class of tryptamines can be unpredictable in their interactions and the NBOMes are known to be unpredictable even alone. This combination is best avoided
  • 2C-x
    • The 5-MeO psychedelics can interact unpredictably to potentiate other psychedelics
  • 2C-T-x
    • Both classes of compounds can be unpredictable alone
  • Cannabis
    • Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.
  • MDMA
    • Some of the 5-MeO tryptamines are a bit unpredictable and should be mixed with MDMA with care

Low risk & Increased Effects

Low risk & Decreased Effects

Low risk & No Synergy

  • Caffeine
    • High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.
  • Opioids