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Caffeine

Basic Information

Summary

Caffeine is a a CNS stimulant, and also the most widely used psychoactive substance in the world. It is legal and unregulated in most parts of the world, and is found in many commonly sold products. It has a good safety profile, though regular heavy use can cause physical dependence and contribute to certain medical conditions.

Stimulant

Stimulants excite the nervous system and increase physiological function.

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Habit-forming

These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.

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Nootropic

Nootropics, otherwise known as "Smart Drugs" or "Cognitive Enhancers," are substances that can improve cognitive function, memory, creativity, motivation and can also aid in decreasing anxiety.

Common

Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.

Dose

Threshold:
Threshold10-20mg
Light20-75mg
Common75mg-250mg
Strong250-400mg
Heavy400mg+

NOTE: The lethal dose for caffeine starts at approximately 3g. The average cup of coffee contains roughly 75-150mg of caffeine.

Duration

All ROAs
Onset5-10 minutes
Duration1.5-5 hours
After-effects3-4 hours

Effects

elevated heartrate, increase in cognitive abilities, physical agitation, panicked thinking, racing thoughts, uncomfortable bodyload

Aliases

coffee

Bioavailability

Orally it varies from around 77%-99%

See TripSit Wiki for more information about drug interactions

Interactions

Caution

  • DOx
    • High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating it may cause some physical discomfort.
  • NBOMes
    • Caffiene can bring out the natural stimulation from psychedelic drugs to make it uncomfortable. High doses can cause anxiety which is hard to handle while tripping
  • ╬▒MT
    • High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.
  • PCP
    • Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.
  • Amphetamines
    • This combination of stimulants is not generally necessary and may increase strain on the heart, as well as potentially causing anxiety and greater physical discomfort.
  • MDMA
    • Caffiene is not really necessary with MDMA and increases any neurotoxic effects from MDMA
  • Cocaine
    • Both stimulants, risk of tachycardia, hypertension, and in extreme cases heart failure.

Low risk & Decreased Effects

Low risk & No Synergy

  • Mushrooms
  • LSD
  • DMT
  • Mescaline
    • High doses of caffeine are uncomfortable and this will be magnified by psychedelics
  • 2C-x
    • High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.
  • 2C-T-x
    • High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.
  • 5-MeO-xxT
    • High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.
  • Cannabis
  • Ketamine
    • No unexpected interactions.
  • MXE
    • No likely interactions
  • DXM
    • High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.
  • N2O
  • Alcohol
  • GHB/GBL
  • Opioids
  • Tramadol
  • MAOIs
  • SSRIs