Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.

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2-FAstimulantresearch chemicalhabit formingcommonStimulant drug of the Amphetamine family. Reported as having Effects similar to those of Dextroamphetamine, but with a milder euphoria and a comparatively smoother comedown. Has a shorter duration and less empathogenic effect-profile as compared with 4-FA. Thought not to have some of the neurotoxic metabolites Amphetamine can produce.
2-FMAstimulantresearch chemicalhabit formingcommonA long-acting stimulant often compared to lisdexamphetamine. Thought not to have some of the neurotoxic metabolites Amphetamine can. Very functional, and for this reason it is frequently used for studying.
25C-NBOMepsychedelicresearch chemicalcommonA relatively new and popular research chemical. A short acting psychedelic related to 2C-C with similar Effects to LSD, though more visual with less of a 'head-trip.' Frequently mis-sold as LSD. Causes an uncomfortable body load and has caused several deaths even within regular dose ranges.
25I-NBOMepsychedelicresearch chemicalcommonA relatively new and popular research chemical with psychedelic properties. Users report an uncomfortable body load with very strong visuals, though with less of a mental aspect than most psychedelics. Commonly mis-sold as LSD, since it is much cheaper to produce. Is considered quite unsafe, and has caused several deaths at 'regular' doses.
2C-BpsychedelicempathogencommonA popular psychedelic in the phenethylamine">Phenethylamine family. Provides empathic experiences at lower doses and strong visual and psychedelic experiences at higher doses. Commonly used as a party drug as it is more clear-headed than most psychedelics. 2C-B has been in use since the early 1990s
2C-Epsychedelicresearch chemicalcommonAn intense psychedelic drug with very strong visuals, sometimes criticised for its relatively uncomfortable body load. Otherwise, Effects are comparable to other 2c-x drugs.
2C-Ipsychedelicresearch chemicalcommonA psychedelic similar to the more well-known 2C-B. Users frequently report very vivid and bright open-eye visuals and more mild closed-eye visuals compared to 2C-B and other drugs in the 2C family. Can also be more stimulating than 2C-B along with having a slight body load for some users. Less safe at high doses compared to 2C-B
3-MeO-PCPdissociativeresearch chemicalhabit formingcommonA potent dissociative often compared to MXE but with a longer duration, much less sedating Effects and causing an overall different experience. Users have reported Effects as being similar to PCP. Roughtly ten times more potent than 4-MeO-PCP.
4-AcO-DMTpsychedelicresearch chemicalcommonA prodrug for Psilocin with extremely similar Effects as Mushrooms.
4-FAstimulantresearch chemicalhabit formingempathogencommonAn empathogen commonly used in place of MDMA. Has about the same duration of empathogenic Effects but a longer stimulant "tail."
4-HO-METpsychedelicresearch chemicalcommonA lesser known psychedelic tryptamine. Functional analogue of Psilocin. Very poorly soluble in water and Alcohol.
5-HTPcommonsupplementThe precursor to serotonin. In some countries it is sold OTC as a supplement for mood stabilisation and insomnia. It is frequently used as a recovery supplement following the use of MDMA or any other drug that depletes serotonin. Do not mix this drug with anything serotonergic, as this can cause serotonin syndrome.
5-MAPBpsychedelicstimulantresearch chemicalempathogenhabit formingcommonAn empathogen structurally similar to MDMA. Typically more visual than MDMA. Often reported to be much less stimulating and more relaxing than most other stimulating empathogens. Less psychedelic than 6-APB. Much longer lasting than MDMA.
5-MeO-MiPTpsychedelicresearch chemicalempathogencommonA potent, stimulating psychedelic tryptamine, sometimes compared to 5-MeO-DiPT. Has an unusually strong body component and weak visual Effects. Often said to be very empathogenic.
AB-FUBINACAresearch chemicalhabit formingtentativecommonArguably the most common synthetic cannabinoid, AB-FUBINACA was originally developed by Pfizer as an analgesic, but has since abandoned for medical use. It has since found a following in the RC community, however it's extremely high potency and inclusion in synthetic blends makes it dangerous, and it has killed in overdose. Exercise caution.
Adderallstimulanthabit formingcommonA mixture of 75% dextroamphetamine and 25% levoamphetamine. Commonly used to treat obesity, narcolepsy and ADHD. It is also used widely either as a recreational stimulant or study-aid, particularly in the USA where it is frequently prescribed.
AL-LADpsychedelicresearch chemicalcommonAL-LAD is a hallucinogenic drug, lysergamide and an analogue of LSD. It is reported as having some subtle experiential differences to LSD (such as increased visuals), and also appears to be slightly shorter lasting. AL-LAD doses are similar to those of LSD, depending on purity. Its availability on the Internet since 2013 has lead to strong popularity among the drug community.
Alcoholdepressant habit formingcommonAlcohol is a CNS depressant that acts through the GABAreceptor, and is one of the most common strong psychoactives used by humans. It has a long history of use and its intoxicating Effects are well-studied and documented. It remains legal in most parts of the world.
Alprazolambenzohabit formingdepressant commonAn extremely common benzodiazepine better known as Xanax, frequently prescribed for the treatment of anxiety and panic disorders. Alprazolam is short-lasting and primarily anxiolytic, though also possesses hypnotic properties. At high doses amnesia and loss of inhibition are common. Do not mix with other depressants.
Amphetaminestimulanthabit formingcommonA very popular CNS stimulant available on prescription and black markets. Recreational in high doses, producing mild euphoria and an abundance of energy. Popular in eastern europe and the US.
ParacetamolcommonA common, over the counter, fever reducer and painkiller. It is mixed with many common opiates. Can cause liver damage and failure in higher doses. No recreational value.
Ashwagandhadepressant supplementcommonIs an Adaptogen. It is commonly used for its ability to prevent anxiety. It also is helpful in relieving insomnia. It's name means "Smell of Horse" due to its smell and the traditional belief that ingesting the this herb will give you the strength and virility of a horse.
AspirincommonA widely used anti-inflammatory and blood-thinner produced by acetylation of the naturally occurring salicyclic acid. Part of the nonsteroidal antiinflammatory class of drugs, a cyclooxygenase inhibitor. Very common over-the-counter pain reliever and fever reducer. Also used in smaller doses to lower risk of heart attack.
βk-2C-Bpsychedelicresearch chemicalcommonA long-acting psychedelic and empathogen with unpredictable effectiveness. Roughly double the duration of 2C-B. Inactivated by high pH.
Caffeinestimulanthabit formingnootropiccommonCaffeine is a a CNS stimulant, and also the most widely used psychoactive substance in the world. It is legal and unregulated in most parts of the world, and is found in many commonly sold products. It has a good safety profile, though regular heavy use can cause physical dependence and contribute to certain medical conditions.
Cannabisdepressant stimulantpsychedelichabit formingcommonA common and widely used psychoactive plant, which is beginning to enjoy legal status for medical and even recreational use in some parts of the world. Usually smoked or eaten, primary Effects are relaxation and an affinity towards food - a state described as being 'stoned.'
CitalopramcommonCitalopram is an SSRI that is used to treat depression. It does not lead to a high and causes a wide range of negative psychological and physical Effects when people attempt to abuse it and can lead to serotonin syndrome and cause suicidal ideation. Those with bipolar disorder tend to go into a mixed state or manic states when trying SSRI's.
Clonazepambenzohabit formingdepressant commonA medium-length common prescription benzodiazepine, often used to treat panic attacks because of its relatively fast sublingual onset. Primarily anxiolytic, but also possessing of other benzo traits.
Clonazolambenzoresearch chemicalhabit formingdepressant commonA long lasting benzodiazepine with heavily hypnotic Effects. The safety profile is not well established, and there have been reports that people taking it three days in a row have had a seizure. Most comparable to Triazolam, but with a much longer half-life.
Clonidinedepressant commonIs a medication that is used to treat high blood pressure, anxiety, withdrawal (Typically from Alcohol, Opioids, Smoking) and many other uses.
Cocainestimulanthabit formingcommonA highly popular, short acting CNS stimulant that works by blocking the reuptake of dopamine, serotonin, and norepinephrine. It is known to increase euphoria, confidence, sex-drive, focus, body temperature, and heart rate. Cocaine can cause severe vasoconstriction and is known to be cardiotoxic and have a high potential for compulsive redosing and addiction.
Codeineopioidhabit formingdepressant commonCodeine is a weaker opioid used to treat mild to moderate pain and to relieve cough. In many countries it is available over the counter in combination with paracetamol, which can easily be extracted to retrieve near-pure Codeine. For this reason, it is used widely as a recreational opioid. It is metabolised into Morphine in the body at a rate of 5% mg for mg.
Cyclobenzaprinedepressant habit formingcommonMuscle relaxant and CNS depressant used to relieve skeletal muscle spasms and associated pain in acute musculoskeletal conditions. Sometimes prescribed off-label for treatment of fibromyalgia or as a sleep aid. Has little recreational value alone, but may potentiate some opioids. May cause drowsiness, dry mouth and dizziness.
Dexedrinestimulanthabit formingcommonA highly abusable stimulant. It is rarely prescribed in the US to treat ADHD, and is very similar in Effects to Adderall, as its main ingredient is 75% of what Adderall is.
Diazepambenzohabit formingdepressant commonA very common and widely prescribed benzodiazepine with hypnotic and sedative qualities. The metre by which other benzodiazepines are compared. May cause amnesia and lowered inhibitions in excess. Has a relatively long half-life in comparison with other benzodiazepines.
DMTpsychedeliccommonA popular and powerful psychedelic, typically used in two ways; either it is vapourised for a short 'breakthrough' experience, or it is taken in combination with an enzyme inhibitor for a long, intense trip (this is also known as Ayahuasca or pharmahuasca).
DOCpsychedelicstimulantresearch chemicalcommonA potent stimulating psychedelic with a long action, a phenethylamine">Phenethylamine and substituted Amphetamine. Sometimes sold as LSD but also enjoyed on its own merits by many. Usually sold on blotters slightly larger than those LSD is found on, but can also be bought in powder form.
DOMpsychedelicstimulantresearch chemicalcommonThe most popular psychedelic Amphetamine due to its pleasant Effects, lower potency and shorter duration. Effects have been described as 'siller' than LSD and related DOX chemicals
DPHdepressant deliriantcommonAn antihistamine which, when taken in smaller doses relieves allergies and insomnia. In larger doses works as a deliriant and can actually keep the user awake. Generally the 'high' of this drug is reported as dysphoric, potentially causing hallucinations indistinguishable from reality.
Dimenhydrinatedepressant deliriantcommonA combination of diphenhydramine and a mild stimulant to counteract the drowsiness accompanied by typical medical use of diphenhydramine. Roughly half the potency of DPH. Small doses can relieve motion sickness, reduce body load from opioids or DXM. Becomes a deliriant in high doses, keeping the user awake and often causing dysphoric, realistic hallucinations.
DXMdissociativehabit formingcommonCommonly found in certain over the counter cough medicines. Has dissociative Effects similar to Ketamine or MXE, though also shares properties with opioids and Alcohol. Make sure DXM is the only active ingredient in the preparation.
Ethylphenidatestimulantresearch chemicalhabit formingcommonPotent psychostimulant, similar to Methylphenidate. Note: Ethylphenidate should NOT be insufflated as it is known to be highly caustic and will cause serious harm to your nasal septum, even with light usage.
Etizolambenzoresearch chemicalhabit formingdepressant commonA thienodiazepine anxiolytic. Similar in action to benzodiazepine drugs. Relieves anxiety, causes sedation and mild euphoria. High doses can lead to losing memory of what happened while on the drug. Users often compulsively re-dose frequently leading to accidental blackouts. Can be found in pressed pharmaceutical pills from various countries, clandestine pill presses, or as a powder
Dexmethylphenidatestimulanthabit formingcommonThe psychoactive isomer of Methylphenidate, mostly used to treat ADHD. Twice as potent as Methylphenidate, and is said to have cleaner psychostimulant Effects with fewer side Effects.
GBLdepressant habit formingcommonA pro-drug to GHB whose rapid absorption leads it to have a faster onset and shorter duration. Used in a similar manner to GHB, as a less-toxic alternative to Alcohol.
GHBdepressant habit formingcommonA euphoric depressant which is prescribed as a sleep aid and sometimes to help with Alcohol detox. Also used as a recreational depressant, as a non-toxic alternative to Alcohol, or to enhance sex.
Heroinopioidhabit formingdepressant commonA powerful opioid drug derived from Morphine, with two to four times the potency. Also known as diacetylmorphine. Infamous for its high addiction potential and fatal respiratory depression in overdose, C. R. Alder Wright first synthesised this compound in 1874 while trying to find a less addictive alternative to Morphine. One of the most popular drugs of all time.
Hydrocodonedepressant opioidhabit formingdepressant commonA Codeine-derived opioid generally unheard of outside the United States. Generally mild in Effects, used as an analgesic and cough-supressant. Sometimes used recreationally.
IbuprofencommonA ubiquitously available pain reliever/fever reducer. Ibuprofen is a nonsteroidal anti-inflammatory drug, available in many forms. It is sometimes used to reduce the body-load caused by certain drugs, such as stimulants.
Ketaminedissociativehabit formingcommonA short acting dissociative anaesthetic and hallucinogen commonly used in emergency medicine. It is the prototypical dissociative, and is widely used at sub-anesthetic doses recreationally. Small doses are comparable with Alcohol, while larger doses are immobilising and lead to psychedelic experiences: the "K-Hole."
Kratomopioidstimulanthabit formingdepressant commonA drug made out of the leaves of Mitragyna Speciosa, which is related to coffee. Stimulating at lower doses, with opioid Effects at higher doses. Frequent heavy use can cause physical addiction and withdrawals.
L-THEANINEcommonsupplementAn Amino acid that is structural similar to Glutamine. Most report it as a relaxing agent without much sedation. Most commonly found tea. Usually mixed with Caffeine.
Lorazepambenzohabit formingdepressant commonAn intermediate acting benzodiazepine commonly known as Ativan, commonly prescribed as an alternative to Xanax. Sedating, hypnotic and anxiolytic. Potential to induce amnesia and lowered inhibitions in overdose. Do not combine with other depressants.
LSApsychedeliccommonA chemical found in Morning Glory and Hawaiian Baby Woodrose seeds, which are often legally available. Has mental Effects similar to LSD, although with almost no visual Effects. It is famous for being very nauseating, and for causing excessive time dilation at higher doses.
LSDpsychedeliccommonLSD is a popular psychedelic with a relatively long history of use and research, and as such is known to be relatively safe despite its extremely high potency. It is the archetypical psychedelic to which all others are compared, and remains in popular usage.
MDApsychedelicstimulantempathogenhabit formingcommonA stimulant and empathogen. Similar to MDMA but typically produces more visuals than MDMA. Known to be more neurotoxic than MDMA, and is a minor metabolite of MDMA. Duration and onset similar to MDMA. The common Marquis reagent test cannot differentiate MDA and MDMA.
MDMAstimulantpsychedelicempathogenhabit formingcommonThe world's most popular empathogen with powerful pro-social Effects. Has been strongly linked to cognitive decline in excess. Popular at parties, it is often sold in powder or in pills, and may be adulterated with other similar chemicals.
MDPVstimulantresearch chemicalhabit formingcommonMDPV is a potent, and extremely compulsive synthetic euphoric stimulant, which shares some empathogenic Effects with MDMA. Has a reputation for causing psychosis. MDPV has been found in products sold as "bath salts", "plant food/fertilizer", and in some "ecstasy."
MelatoninnootropiccommonsupplementA naturally occurring hormone produced in the body, which promotes sleep at certain times in the day based on the circadian rhythm. It is also commonly available as a drug to treat insomnia and promote a proper sleep cycle. It can be used to promote sleepfulness at the tail-end of drug experiences, though it is not particularly hypnotic.
MescalinepsychedeliccommonA psychedelic of the phenethylamine">Phenethylamine family. Found in psychedelic cacti that have long been used by peoples native to the Southwestern US and Mexico, including Peyote and San Pedro cacti, among others. Can be found as cactus pulp, as an extract from cacti, or as a synthetic substance created in a lab.
Methadoneopioidhabit formingdepressant commonA synthetic opioid drug used as an analgesic and is often used in detoxification off of other opioids. As it has a much longer half-life.
Methamphetaminestimulanthabit formingcommonA fairly common and very strong CNS stimulant. It is sometimes prescribed in the form of desoxyn for ADHD and severe obesity. In low doses, Methamphetamine can elevate mood, increase alertness, concentration, energy and reduces appetite. At higher doses, it can induce mania, psychosis and muscle degeneration among other issues. Tolerant users may report much higher doses than new users.
Methylonestimulantpsychedelicresearch chemicalhabit formingempathogencommonβk-MDMA is a cathinone stimulant and empathogen, similar in structure to MDMA, though more stimulating and less empathogenic in comparison. Was very commonly mis-sold as MDMA on the street until it was banned in 2013. The Marquis reagent can differentiate βk-MDMA from MDMA. Less potent than MDMA with a slightly shorter duration.
Methylphenidatestimulanthabit formingcommonA psychostimulant commonly used in the treatment of ADHD, narcolepsy and obesity, particularly in the EU instead of Adderall. Methylphenidate is also a 5HT1A receptor agonist. Sometimes prescribed off-label to help the withdrawals from Cocaine and other stimulants.
Modafinilstimulanthabit formingnootropiccommonA wakefulness promoting, long acting stimulant which is typically only used functionally, because there is no real euphoric component to its Effects. Also prescribed for daytime sleeping disorders.
Morphineopioiddepressant habit formingdepressant commonThe prototypical opioid drug, a powerful analgesic with euphoric qualities, found in the seeds and wax of the plant papaver somniferum (Opium poppy). First isolated by Friedrich Sertürner in 1805, named for its sleep-inducing qualities. Do not combine with other depressants, may cause dangerous respiratory depression in overdose.
MPAstimulantresearch chemicalhabit formingcommonAn analogue of Methamphetamine with Effects close to amphetamine. Some users report negative side Effects including stomach discomfort and sweating. Acts as a selective NDRI.
MushroomspsychedeliccommonFungi containing psilocybin, a prototypical psychedelic with similar Effects to LSD, but with a shorter duration; also considered as being more confusing, introspective and entheogenic. Usually refers to psilocybe Mushrooms rather than Amanitas, which have different Effects. Are considered physically safe if properly identified, which should always be done by an expert.
NaproxencommonA very common pain reliever/fever reducer also known as Aleve. Naproxen is in the same category as Ibuprofen, which is also a nonsteroidal anti-inflammatory. This drug is available in most places over the counter. Is sometimes used to reduce the body-load of certain drugs.
Nicotinestimulanthabit formingnootropiccommonA chemical found in tobacco, aubergines and tomatoes which is considered one of the most addictive drugs in existence. It is a mild stimulant, with stress relieving Effects. It is widely used in the form of cigarettes, the use of which carries a high risk of causing cancer or heart issues over time. Increasingly, it is 'vaped' as a purportedly safer alternative to smoking.
N2Odissociativehabit formingcommonN2O oxide, also known as laughing gas, often inhaled through balloons filled with canisters of the gas.. A short-acting dissociative inhalant with strong visual, mental and auditory Effects. Extremely popular especially in combination with other drugs.
Opiumopioidhabit formingdepressant commonOpium is a naturally occurring analgesic harvested as a latex from ripe Papaver somniferum (Opium poppy) pods. The sap of the poppy plant primarily contains Codeine and Morphine with the amounts varying by plant, which can be made into a tea and consumed raw, or further processed.
Oxycodoneopioidhabit formingdepressant commonA semisynthetic opioid analgesic developed in 1917, prescribed primarily for pain management. It has become extremely popular as a recreational drug in some areas, and carries a high potential for addiction. Sometimes known as 'hillbilly Heroin,' somewhat paradoxically since it is rather expensive. Reported as being a little more 'stimulating' than other opioids.
PeyotepsychedeliccommonPeyote is a small, spineless cactus that contains Mescaline as its primary active chemical. It has a long history of use among the natives of northern Mexico and SW United States.
Pregabalindepressant habit formingcommonPregabalin (Lyrica) is a GABA derivative that is used to treat neuropathic pain and seizures, as well as anxiety.
PromethazinecommonA first generation antihistamine, which also possesses anticholinergic, strong sedative and antipsychotic properties. Once commonly used as a treatment for psychosis, it is now more commonly seen as a component of Codeine cough syrups as an anti-nausea agent.
Propranololdepressant commonIs a nonselective beta blocker. It is used in medication for high blood pressure, anxiety, and tremors. Also fun fact, it was the first successful beta-blocker developed.
Propylhexedrinestimulanthabit formingcommonA relatively common CNS stimulant sold over the counter in benzedrex inhalers.
PseudoephrinestimulantcommonWidely sold as a decongestant, and one isomer of Ephedrine. It is not generally considered to have any recreational value. Is also used in the synthesis of Methcathinone and Methamphetamine.
PSTopioiddepressant habit formingcommonPoppy Tea can be made from poppy pods, stalks and seeds, and contains various Opium alkaloids including primarily Morphine, as well as Codeine and others. There is great variation in Poppy Tea potency and therefor doses are indicated for opioid naive users.
Salviadissociativedeliriantdepressant commonA plant which, when smoked, causes short but very intense psychedelic experiences. It is considered physically safe, though users of high dosages often experience bizarre other-worldly scenarios which may be confusing or terrifying.
Sonatadepressant habit formingcommonSedative-Hypnotic of the nonbenzodiazepine from the Pyrazolopyramide class. It is used mostly for short term insomnia.
Tramadolopioidhabit formingdepressant commonA synthetic opioid analgesic, Tramadol is used to treat moderate pain and can be considered a medium-strength opioid. Tramadol also has the unusual effect of being a serotonin releasing agent and a serotonin reuptake inhibitor, and as a consequence should not be taken in excess due to the risk of serotonin syndrome. Risk of seizures above 300mg doses.
Vyvansestimulanthabit formingcommonAlso known as lisdexamphetamine, this drug is a CNS stimulant often prescribed for ADHD, narcolepsy and obesity. It is also a pro-drug for dextroamphetamine, and functions as a method for providing extended-release stimulation. It is sometimes prescribed alongside an SSRI for depression.
YERBA-MATEcommonstimulanthabit formingnootropicIs marketed for its ability to suppress appetite and burn fat. Yet only with high doses. It has a quite high ratio of Caffeine. It has anti-inflammatory properties.
Zolpidemdepressant habit formingcommonCommonly prescribed for insomnia, Ambien (Zolpidem) can cause realistic hallucinations similar to those of deliriants, and is very likely to cause amnesia at higher doses. Take care when using this drug, as it tends to lower inhibitions to a level which causes the user to do things they might not normally do when sober.
Zopiclonedepressant habit formingcommonA nonbenzodiazepine sedative sleep aid (Z-drug), which can have hallucinogenic Effects if taken while awake. Often causes users to have a metallic taste in the mouth for ~12h. Has been reported in some cases to cause certain users to black out, redose excessively and undertake dangerous activities such as driving.

Factsheets on 87 drugs