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Clomethiazole

Basic Information

Summary

Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute Alcohol withdrawal.

Depressant

Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.

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Research Chemical

Research chemicals are drugs with relatively little history of human use, and thus particular care should be taken if choosing to ingest them.

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Habit-forming

These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.

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Tentative

Drugs marked as tentative are those our team wasn't able to find much reliable information about. This is often because the drug is very new. Information listed under these drugs should not be entirely trusted.

Dose
Threshold100mg
Light100-150mg
Common150-200mg
Heavy200mg+
Duration
All ROAs
Onset15-40 minutes
Duration5-8 hours
After-effects1-16 hours
Effects

    Effects lovingly provided by PsychonautWiki

    WarningThe normal amount in capsules is 192mg's. Treat this more as a barbiturate than a benzodiazepine, as the toxicology for this substance is rather lacking.
    EffectsAnxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.
    See TripSit Wiki for more information about drug interactions

    Interactions

    No interaction information for Clomethiazole