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Cyclizine

Basic Information

Summary

First generation antihistamine and anticholinergic drug used to combat nausea and vomiting. Causes drowsiness. Like most antihistamines in high doses it induces delirium and vivid realistic hallucinations. Probably uncomfortable and not enjoyable.

Depressant

Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.

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Dose

Oral
Common25-50mg

NOTE: The provided dosages are intended for therapeutic use.

Duration

All ROAs
Onset10-30 minutes
DurationOral hours
After-effects14 hours

Side-effects

drowsiness, dry mouth, headache, psychomotor impairment, urinary retention, blurred vision, dermatitis, and gastrointestinal disturbances

Chemistry

IUPAC: 1-benzhydryl-4-methyl-piperazine | Formula: C18H22N2 | Molecular Mass: 266.381 g/mol | Water Solubility: 1000 mg/L (25 °C)

Pharmacodynamics

H1 receptor inverse agonist; mACh receptor antagonist

See TripSit Wiki for more information about drug interactions

Interactions

No interaction information for Cyclizine