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MDMA

Basic Information

Summary

The world's most popular empathogen with powerful pro-social effects. Has been strongly linked to cognitive decline in excess. Popular at parties, it is often sold in powder or in pills, and may be adulterated with other similar chemicals.

Stimulant

Stimulants excite the nervous system and increase physiological function.

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Psychedelic

Psychedelics are drugs which alter the perception, causing a number of mental effects which manifest in many forms including altered states of consciousness, visual or tactile effects.

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Habit-forming

These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.

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Common

Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.

Dose

Oral
Light40-75mg
Common75-125mg
Strong125-175mg
Heavy175mg+
Insufflated/Rectal
Light30-70mg
Common70-120mg
Strong120-165mg
Heavy165mg+

NOTE: Higher doses increase neurotoxic effects

Duration

All ROAs
Onset20-70 minutes
Duration3-5 hours
After-effects1-72 hours

Detection

1-3 days single use, 3-5 days heavy use

Aliases

molly
ecstasy
adam
xtc
mandy
x
md

Marquis

Black (may have purple tint)

General-advice

Only roll every 2-3 months.

Wiki

http://wiki.tripsit.me/wiki/MDMA

See TripSit Wiki for more information about drug interactions

Interactions

Dangerous

  • ╬▒MT
  • DXM
  • Tramadol
    • Tramadol and stimulants both increase the risk of seizures.
  • MAOIs
    • MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably. MAO-A inhibitors with MDMA will lead to hypertensive crises.

Unsafe

  • PCP
    • This combination can easily lead to hypermanic states

Caution

  • DOx
    • The combined stimulating effects of the two can be uncomfortable. Coming down on the MDMA while the DOx is still active can be quite anxiogenic.
  • NBOMes
  • 2C-T-x
  • 5-MeO-xxT
    • Some of the 5-MeO tryptamines are a bit unpredictable and should be mixed with MDMA with care
  • MXE
    • There have been reports of risky serotonergic interactions when the two are taken at the same time, but MXE taken to the end of an MDMA experience does not appear to cause the same issues.
  • Cocaine
    • Cocaine blocks some of the desirable effects of MDMA while increasing the risk of heart attack.
  • Caffeine
    • Caffiene is not really necessary with MDMA and increases any neurotoxic effects from MDMA
  • Alcohol
    • Both MDMA and alcohol cause dehydration. Approach this combination with caution, moderation and sufficient hydration. More than a small amount of alcohol will dull the euphoria of MDMA
  • GHB/GBL
    • Large amounts of GHB/GBL may overwhelm the effects of MDMA on the comedown.

Low risk & Increased Effects

  • Mushrooms
  • LSD
  • DMT
  • Mescaline
  • 2C-x
  • Cannabis
    • Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible.
  • Ketamine
    • No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.
  • N2O
  • Amphetamines
    • Amphetamines increase the neurotoxic effects of MDMA

Low risk & Decreased Effects

Low risk & No Synergy

References & Notes

General