A chemical found in tobacco, aubergines and tomatoes which is considered one of the most addictive drugs in existence. It is a mild stimulant, with stress relieving effects. It is widely used in the form of cigarettes, the use of which carries a high risk of causing cancer or heart issues over time. Increasingly, it is 'vaped' as a purportedly safer alternative to smoking.
Stimulants excite the nervous system and increase physiological function.Read more on TripSit Wiki...
These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.Read more on TripSit Wiki...
Nootropics, otherwise known as "Smart Drugs" or "Cognitive Enhancers," are substances that can improve cognitive function, memory, creativity, motivation and can also aid in decreasing anxiety.
Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.
Effects lovingly provided by PsychonautWiki
- The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of amphetamine can easily lead to thought loops. Coming down from amphetamines while the DOx is still active can be quite anxiogenic.
- Amphetamines and NBOMes both provide considerable stimulation. When combined they can result in tachycardia, hypertension, vasoconstriction and in extreme cases heart failure. The anxiogenic and focusing effects of stimulants are also not good in combination with psychedelics as they can lead to unpleasant thought loops. NBOMes are known to cause seizures and stimulants can increase this risk.
- Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences. In extreme cases, they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.
- The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.
- Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues.
- This combination can easily lead to hypermanic states
- The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops
- The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally uneccessary because of the stimulating effects of psychedelics. Combination of the stimulating effects may be uncomfortable.
- No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.
- Risk of tachycardia, hypertension, and manic states
- This combination of stimulants will increase strain on the heart. It is not generally worth it as cocaine has a mild blocking effect on dopamine releasers like amphetamine
- This combination of stimulants is not generally necessary and may increase strain on the heart, as well as potentially causing anxiety and greater physical discomfort.
- Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol and the stimulant less. Extended release formulations may severely impede sleep, further worsening the hangover.
- Stimulants increase respiration rate allowing a higher dose of sedatives. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.
- Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.
Low risk & Decreased Effects
- Both can dull each other's effects, so if one wears off before the other it's possible to overdose due to the lack of counteraction
Low risk & No Synergy
References & Notes
- Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. -https://www.ncbi.nlm.nih.gov/pubmed/22232050
- Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. - https://www.ncbi.nlm.nih.gov/pubmed/22232050
- Site of nicotine absorption from a vapour inhaler--comparison with cigarette smoking - http://www.ncbi.nlm.nih.gov/pubmed/10663452
- Brand differences of free-base nicotine delivery in cigarette smoke: the view of the tobacco industry documents - http://www.ncbi.nlm.nih.gov/pubmed/16728749
- Exposure to nicotine produces an increase in dopamine D2(High) receptors: a possible mechanism for dopamine hypersensitivity. - http://www.ncbi.nlm.nih.gov/pubmed/20942582
- Tobacco leaf, smoke and smoking, MAO inhibitors, Parkinson's disease and neuroprotection are there links? - http://www.ncbi.nlm.nih.gov/pubmed/14697903
- Brand differences of free-base nicotine delivery in cigarette smoke: the view of the tobacco industry documents. - http://www.ncbi.nlm.nih.gov/pubmed/16728749
- Do electronic cigarettes impart a lower potential disease burden than conventional tobacco cigarettes? Review on E-cigarette vapor versus tobacco s... - http://www.ncbi.nlm.nih.gov/pubmed/25302452
- The impact of caffeine use on tobacco cessation and withdrawal. - http://www.ncbi.nlm.nih.gov/pubmed/9022872