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Quetiapine

Basic Information

Summary

An atypical antipsychotic medication under the brand name Seroquel. Also used to treat insomnia and mood swings. This drug is very sedating and can stop/slow down psychedelic drug trips. Infrequently abused.

Depressant

Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.

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Dose
Light25mg-50mg
Common50mg-150mg
Strong150mg-300mg
Heavy300mg-800mg
Duration
All ROAs
OnsetOral minutes
Duration7-12 hours
After-effectsCan hours
Effects

    Effects lovingly provided by PsychonautWiki

    Adverse-effectsdizziness, fatigue, extrapyramidal symptoms, increased diastolic blood pressure, increased triglycerides, increased total cholesterol, increased appetite, constipation, dry mouth, headache, and somnolence
    Drug-contradictionsapomorphine, bromocriptine, cabergoline, carbamazepine, cimetidine, clarithromycin, dabrafenib, dopamine, erythromycin, idelalisib, itraconazole, ivacaftor, ketoconazole, levodopa, lisuride, mefloquine, methyldopa, nefazodone, ondansetron, panobinostat, pramipexole, rifabutin, rifampin, ropinirole, sodium oxybate, st. john's wort, vilanterol, and vemurafenib
    Overdose-symptomssedation, hypotension, tachycardia, cardiac arrhythmia, coma, and death
    PharmacologyD1, D2, D3, and D4 receptor antagonist; 5-HT1A receptor partial agonist; 5-HT2A, 5-HT2C, and 5-HT7 receptor antagonist; α1-adrenergic and α2-adrenergic receptor antagonist; H1 receptor antagonist; mACh receptor antagonist
    Aliasesseroquel
    Effectssedation, dizziness, fatigue, constipation, dry mouth, headache, appetite change, increased blood pressure
    ChemistryIUPAC: 2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol | Formula: C21H25N3O2S | Molecular Mass: 383.5099 g/mol | Solubility in Water: 3.29 mg/mL (20 °C)
    LegalAustralia: Prescription Only (S4) | United Kingdom: POM | United States: ?-only
    See TripSit Wiki for more information about drug interactions

    Interactions

    No interaction information for Quetiapine