A nonbenzodiazepine sedative sleep aid (Z-drug), which can have hallucinogenic effects if taken while awake. Often causes users to have a metallic taste in the mouth for ~12h. Has been reported in some cases to cause certain users to black out, redose excessively and undertake dangerous activities such as driving.
Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.Read more on TripSit Wiki...
These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.Read more on TripSit Wiki...
Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.
Effects lovingly provided by PsychonautWiki
|Effects||Lethargy, tiredness, a dreamlike state while awake, can induce heavy sleep.|
|Contraindictions||Liver disease, myasthenia gravis, severe chronic bronchitis, emphysema, sleep apnea, thyroid gland abnormalities, trimipramine, caffeine, alcohol, erythromycin, itraconazole, rifampicin, phenytoin, carbamazepine, ketoconazole, sulfaphenazole, and nefazodone|
|Chemistry||IUPAC: (RS)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate | Formula: C17H17ClN6O3 | Molecular Mass: 388.808 g/mol|
|Pharmacology||GABA-A receptor positive allosteric modulator; Benzodiazepine receptor agonist|
|Pharmacokinetics||Protein Binding: 45 - 80% | Metabolism: various cytochrome P450 liver enzymes | Excretion: respiration (~50%) and urine (7 - 10 %)|
|Legal||Australia: Prescription Only (S4) | United Kingdom: Controlled Drug (POM) | United States: Schedule IV|
No interaction information for Zopiclone
References & Notes
- Dependence potential of zopiclone studied in monkeys - http://www.ncbi.nlm.nih.gov/pubmed/6892368