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5-HTP
Basic Information
Summary
The precursor to serotonin. In some countries it is sold OTC as a supplement for mood stabilisation and insomnia. It is frequently used as a recovery supplement following the use of MDMA or any other drug that depletes serotonin. Do not mix this drug with anything serotonergic, as this can cause serotonin syndrome.
Common
Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.
Dose
| Therapeutic | |
|---|---|
| Common | 50-100mg |
| Sleep | |
|---|---|
| Common | 100-200mg |
| Recovery | |
|---|---|
| Common | 200-300mg |
NOTE: Do not take this while on a serotonergic drug, only afterwards. Wait at least 12 hours following the last dose in the case of MDMA.
Duration
| All ROAs | |
|---|---|
| Onset | 30-60 minutes |
| Duration | 4-6 hours |
Effects
sleep aid, antidepressant, appetite suppressant, nausea, mood stabilising
Avoid
Anything which interacts with serotonin. Including SSRIs, MAOIs, DXm, MDMA (during or before)
Aliases
5htp
5-hydroxytryptophan
tryptophan
l-tryptophan
oxitriptan
Mdma
5-HTP should only be taken at least 12 hours following an MDMA dose. Do not take it during or before MDMA - this can cause serotonin syndrome.
Interactions
No interaction information for 5-HTP