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Fentanyl

fentanyl

Basic Information

Summary

Fentanyl is a synthetic opiate analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors and is historically used to treat breakthrough pain. Fentanyl is approximately 100 times more potent than Morphine, and is commonly used as a patch. Sometimes used as an adulterant for heroin, which has led to many overdose deaths.

Opioid

Opioids are pain-killing depressants which may also cause euphoria.

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Habit-forming

These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.

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Depressant

Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.

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Dose

Intranasal
Light10-25ug
Common25-50ug
Strong50-75ug+
Transdermal
Light12.5ug/hr
Common25-50ug/hr
Strong50-100ug/hr

NOTE: Due to Fentanyl's high potency, it is incredibly difficult to measure safely, and so can easily lead to overdose.

Duration

Transdermal
Onset90-180 minutes
Duration48-72 hours
After-effectsRisk
Buccal
Onset15-30 minutes
Duration1-4 hours
After-effectsRisk
Insufflated
Onset5-15 minutes
Duration1-4 hours
After-effectsRisk

Aliases

fent

Bioavailability

Sublingual/Buccal 50% | Insufflated 70% | Transdermal 92%

Effects

Analgesia, euphoria, feelings of relaxation, sedative effects, changes in focus, attention, respiratory depression, nausea, constipation, dry mouth, somnolence, confusion, weakness, sweating, fatigue, dizziness, anxiety

Warning

Risk of post-acute withdrawal effects, including depression, anxiety disorder, psychosis, suicidal ideation in extreme cases.

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Interactions