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Aspirin
Basic Information
Summary
A widely used anti-inflammatory and blood-thinner produced by acetylation of the naturally occurring salicyclic acid. Part of the nonsteroidal antiinflammatory class of drugs, a cyclooxygenase inhibitor. Very common over-the-counter pain reliever and fever reducer. Also used in smaller doses to lower risk of heart attack.
Common
Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.
Dose
| Oral | |
|---|---|
| Threshold | 50mg |
| Light | 75mg-81mg |
| Common | 325mg-650mg |
| Heavy | 1.6g |
NOTE: Aspirin is known to be dangerous in dosages of 4g and above
Duration
| All ROAs | |
|---|---|
| Onset | 30-90 minutes |
| Duration | Dose-Dependent |
Effects
Analgesia, Antipyresis, Anti-inflammation, Antiaggregation
Avoid
Acetazolamide, Ammonium Chloride, Alcohol, Tolbutamide, Chlorpropamide, Warfarin, Methotrexate, Phenytoin, Probenecid, Valproic Acid, Other NSAIDs, Corticosteroids, Spironolactone, Penicillin G, Vitamin C
Aliases
acetylsalicylate
Bioavailability
Oral: 55.8-74%.
Interactions
No interaction information for Aspirin