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Clomethiazole
Basic Information
Summary
Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal.
Depressant
Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.
Read more on TripSit Wiki...Research Chemical
Research chemicals are drugs with relatively little history of human use, and thus particular care should be taken if choosing to ingest them.
Read more on TripSit Wiki...Habit-forming
These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.
Read more on TripSit Wiki...Tentative
Drugs marked as tentative are those our team wasn't able to find much reliable information about. This is often because the drug is very new. Information listed under these drugs should not be entirely trusted.
Dose
| Oral | |
|---|---|
| Threshold | 100mg |
| Light | 100-150mg |
| Common | 150-200mg |
| Heavy | 200mg+ |
Duration
| All ROAs | |
|---|---|
| Onset | 15-40 minutes |
| Duration | 5-8 hours |
| After-effects | 1-16 hours |
Warning
The normal amount in capsules is 192mg's. Treat this more as a barbiturate than a benzodiazepine, as the toxicology for this substance is rather lacking.
Effects
Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.
Interactions
No interaction information for Clomethiazole