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Delorazepam

delorazepam

Basic Information

Summary

Also known as chlordesmethyldiazepam, this uncommon benzodiazepine compound is primarily used for treatment of anxiety and alcohol withdrawal, due to its long half-life (60-140 hours). It is also the active metabolite of diclazepam and cloxazolam.

Benzodiazepine

Benzodiazepines are generally hypnotic or anxiolytic depressant drugs.

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Habit-forming

These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.

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Depressant

Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.

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Dose

Oral
Light0.25-0.5mg
Common0.5-1.5mg
Strong1.5-2mg
Heavy2-3mg

NOTE: Higher doses increase the chances of blacking out. 1mg Delorazepam is approximately equal to 10mg Diazepam.

Duration

All ROAs
Onset30-60 minutes
Duration12-16 hours
After-effects72 hours

Avoid

All other CNS depressants.

Effects

Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.

Aliases

nordiclazepam

See TripSit Wiki for more information about drug interactions

Interactions

Dangerous

  • Alcohol
    • Ethanol ingestion may potentiate the CNS effects of many benzodiazepines. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Blacking out and memory loss is almost certain.
  • GHB/GBL
    • The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position.
  • Opioids
    • Central nervous system and/or respiratory-depressant effects may be additively or synergistically present. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position Blackouts/memory loss likely
  • Tramadol
    • Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present. Vomit aspiration a risk when passed out, lay down in recovery position if ingested.

Caution

  • Ketamine
    • Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position.
  • MXE
    • Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess.
  • DXM
    • Small doses of benzos can end a bad trip, but both substances potentiate the ataxia and sedation caused by the other and this can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position.

Unsafe

  • PCP
    • Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely

Low Risk & Increased Effects

Low Risk & No Increased Effects

Low Risk & Decreased Effects