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Kratom
Basic Information
Summary
A drug made out of the leaves of Mitragyna Speciosa, which is related to coffee. Stimulating at lower doses, with opioid effects at higher doses. Frequent heavy use can cause physical addiction and withdrawals.
Opioid
Opioids are pain-killing depressants which may also cause euphoria.
Read more on TripSit Wiki...Stimulant
Stimulants excite the nervous system and increase physiological function.
Read more on TripSit Wiki...Habit-forming
These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.
Read more on TripSit Wiki...Depressant
Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.
Read more on TripSit Wiki...Common
Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.
Dose
| Light: | |
|---|---|
| Light | 0.5-1.5g |
| Common | 1.5-3g |
| Strong | 3-6g |
Note: This is for plain leaf only. Some users experience stronger effects from lower doses compared to higher doses. It also is very different person to person, just use this as an outline, as it will change batch to batch and even dose to dose.
Duration
| All ROAs | |
|---|---|
| Onset | 10-40 minutes |
| Duration | 2-5 hours |
| After-effects | 1-12 hours |
Effects
Simultaneous stimulation & sedation. Feelings of empathy. Feelings of euphoria. Aphrodisiac qualities for some people. Vivid waking dreams. Useful with physical labor
Detection
Kratom use is not detected by typical drug screening tests, but its metabolites can be detected by more specialized testing.
Interactions
Dangerous
- Ketamine
- Both substances bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.
- MXE
- This combination can potentiate the effects of the opioid
- DXM
- CNS depression, difficult breathing, heart issues, hepatoxic, just very unsafe combination all around. Additionally if one takes dxm, their tolerance of opiates goes down slightly, thus causing additional synergistic effects.
- Cocaine
- Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.
- Alcohol
- Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely
- GHB/GBL
- The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position
- Tramadol
- Concomitant use of tramadol increases the seizure risk in patients taking other opioids. These agents are often individually epileptogenic and may have additive effects on seizure threshold during coadministration. Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present
- Benzodiazepines
- Central nervous system and/or respiratory-depressant effects may be additively or synergistically present. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position Blackouts/memory loss likely
Caution
- PCP
- PCP can reduce opioid tolerance, increasing the risk of overdose
- N2O
- Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.
- Amphetamines
- Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.
- MAOIs
- Coadministration of monoamine oxidase inhibitors (MAOIs) with certain opioids has been associated with rare reports of severe and fatal adverse reactions. There appear to be two types of interaction, an excitatory and a depressive one. Symptoms of the excitatory reaction may include agitation, headache, diaphoresis, hyperpyrexia, flushing, shivering, myoclonus, rigidity, tremor, diarrhea, hypertension, tachycardia, seizures, and coma. Death has occurred in some cases.
Low Risk & Increased Effects
Low Risk & No Increased Effects
- Mushrooms
- LSD
- DMT
- Mescaline
- DOx
- No unexpected interactions.
- NBOMes
- 2C-x
- 2C-T-x
- No expected interactions, some opioids have serotonin action, and could lead to Serotonin Syndrome or a seizure. These are pretty much only to Pentazocine, Methadone, Tramadol, Tapenatdol.
- αMT
- No unexpected interactions
- 5-MeO-xxT
- MDMA
- Caffeine
- SSRIs
- There have been very infrequent reports of a risk of serotonin syndrome with this combination, though this should not be a practical concern.