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Quetiapine
Basic Information
Summary
An atypical antipsychotic medication under the brand name Seroquel. Also used to treat insomnia and mood swings. This drug is very sedating and can stop/slow down psychedelic drug trips. Infrequently abused.
Depressant
Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.
Read more on TripSit Wiki...Dose
| Oral | |
|---|---|
| Light | 25mg-50mg |
| Common | 50mg-150mg |
| Strong | 150mg-300mg |
| Heavy | 300mg-800mg |
Duration
| Oral | |
|---|---|
| Onset | IR minutes |
| Duration | 7-12 hours |
| After-effects | Can hours |
Adverse-effects
dizziness, fatigue, extrapyramidal symptoms, increased diastolic blood pressure, increased triglycerides, increased total cholesterol, increased appetite, constipation, dry mouth, headache, and somnolence
Drug-contradictions
apomorphine, bromocriptine, cabergoline, carbamazepine, cimetidine, clarithromycin, dabrafenib, dopamine, erythromycin, idelalisib, itraconazole, ivacaftor, ketoconazole, levodopa, lisuride, mefloquine, methyldopa, nefazodone, ondansetron, panobinostat, pramipexole, rifabutin, rifampin, ropinirole, sodium oxybate, st. john's wort, vilanterol, and vemurafenib
Overdose-symptoms
sedation, hypotension, tachycardia, cardiac arrhythmia, coma, and death
Pharmacology
D1, D2, D3, and D4 receptor antagonist; 5-HT1A receptor partial agonist; 5-HT2A, 5-HT2C, and 5-HT7 receptor antagonist; α1-adrenergic and α2-adrenergic receptor antagonist; H1 receptor antagonist; mACh receptor antagonist
Aliases
seroquel
Effects
sedation, dizziness, fatigue, constipation, dry mouth, headache, appetite change, increased blood pressure
Chemistry
IUPAC: 2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol | Formula: C21H25N3O2S | Molecular Mass: 383.5099 g/mol | Solubility in Water: 3.29 mg/mL (20 °C)
Legal
Australia: Prescription Only (S4) | United Kingdom: POM | United States: ?-only
Interactions
No interaction information for Quetiapine